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Medical Practice

Dr. C. Richard Boland
Dr. C. Richard Boland. Expert op het gebied van darmkanker. Biografie. 0

1. Dr. C. Richard Boland. Expert op het gebied van darmkanker. Biografie. 0

Dr. C. Richard Boland, MD, details his pivotal research on hereditary colon cancer, career spanning over 40 years, and influential leadership roles including presidency of...

Erfelijke darmkanker. Lynch syndroom diagnose. 1

2. Erfelijke darmkanker. Lynch syndroom diagnose. 1

Dr. C. Richard Boland, MD, explains how this genetic condition increases cancer risk, the importance of early diagnosis through genetic testing, and why regular screening...

Symptomen van darmkanker. Tekenen van colorectale kanker. 2

3. Symptomen van darmkanker. Tekenen van colorectale kanker. 2

Dr. C. Richard Boland, MD, explains the often silent symptoms of colon cancer, differences between proximal and distal tumor presentations, and how regular screening prevents...

Familiaire darmkanker. Dikkedarmkanker genetische oorzaak. 3

4. Familiaire darmkanker. Dikkedarmkanker genetische oorzaak. 3

Dr. C. Richard Boland, MD, explains how familial colon cancer syndromes develop through different genetic pathways, including Lynch syndrome, adenomatous polyposis, and rare conditions like...

Familiaire darmkanker. Leeftijd bij aanvang. Hoe erfelijke darmkanker te voorkomen? 4

5. Familiaire darmkanker. Leeftijd bij aanvang. Hoe erfelijke darmkanker te voorkomen? 4

Dr. C. Richard Boland, MD, explains how hereditary colon cancer develops earlier than sporadic cases due to inherited gene mutations, why family history and biomarkers...

Prognose van colorectale kanker. Epigenetica. DNA-methylatie belang. 5

6. Prognose van colorectale kanker. Epigenetica. DNA-methylatie belang. 5

Dr. C. Richard Boland, MD, explains how DNA methylation drives 30-40% of cancers through silencing tumor suppressor genes, with specific focus on the CpG Island...

Prognose van colorectale kanker. DNA-methylatie en microRNA-niveaus voorspellen de overleving van kanker 6

7. Prognose van colorectale kanker. DNA-methylatie en microRNA-niveaus voorspellen de overleving van kanker 6

Dr. C. Richard Boland, MD, explains how DNA methylation patterns and microRNA levels serve as powerful biomarkers for predicting cancer prognosis and personalizing treatment. His...

Colorectale kanker. Precisie geneeskunde therapie. Microsatelliet instabiliteit. 7

8. Colorectale kanker. Precisie geneeskunde therapie. Microsatelliet instabiliteit. 7

Dr. C. Richard Boland, MD, explains how microsatellite instability (MSI) impacts treatment selection and prognosis in colon cancer. He details how 15% of colorectal tumors...

Immunotherapie voor colorectale kanker. Keytruda. Pembrolizumab. 8

9. Immunotherapie voor colorectale kanker. Keytruda. Pembrolizumab. 8

Dr. C. Richard Boland, MD, explains how microsatellite instability (MSI) testing transforms treatment selection, why immune checkpoint inhibitors like Keytruda (pembrolizumab) outperform chemotherapy for MSI-high...

Colorectale kanker en ontsteking. Colitis ulcerosa en kankerrisico. 9

10. Colorectale kanker en ontsteking. Colitis ulcerosa en kankerrisico. 9

Dr. C. Richard Boland, MD, explains how chronic inflammation dramatically increases cancer risk throughout the digestive system, particularly in conditions like ulcerative colitis, primary sclerosing...

Virale infectie en colorectale kanker. 10

11. Virale infectie en colorectale kanker. 10

Dr. C. Richard Boland, MD, explores the potential link between viral infections and colon cancer development, discussing the JC virus hypothesis, research challenges, and why...

Curcumine voorkomt darmkanker. Kurkuma dosis om kanker te voorkomen. 11

12. Curcumine voorkomt darmkanker. Kurkuma dosis om kanker te voorkomen. 11

Dr. C. Richard Boland, MD, explains how curcumin—the active compound in turmeric—reduces inflammation and may prevent colon cancer. Research shows populations consuming 300 mg daily...

Kanker chemotherapie precisie geneeskunde. Berekende behandeling. Deel 1. 12

13. Kanker chemotherapie precisie geneeskunde. Berekende behandeling. Deel 1. 12

Dr. C. Richard Boland, MD, explains how calculated chemotherapy treatment using mathematical modeling can overcome tumor resistance and improve cure rates for colorectal cancer, melanoma,...

Kanker chemotherapie precisie geneeskunde. Berekende behandeling. Deel 2. 13

14. Kanker chemotherapie precisie geneeskunde. Berekende behandeling. Deel 2. 13

Dr. C. Richard Boland, MD, explains how mathematical modeling transforms chemotherapy selection from trial-and-error to precision-calculated treatment, using tumor proliferation rates, death rates, and mutation...

Markers voor colorectale kankertumoren. Voorspelling van de werkzaamheid van kankertherapie. 14

15. Markers voor colorectale kankertumoren. Voorspelling van de werkzaamheid van kankertherapie. 14

Dr. C. Richard Boland, MD, explains how the miR-21 microRNA tumor marker revolutionizes colon cancer screening and prognosis. This blood-based biomarker helps identify high-risk patients...

Screening op colorectale kanker. MicroRNA in bloed en ontlasting. Hoe vroege darmkanker te vinden 15

16. Screening op colorectale kanker. MicroRNA in bloed en ontlasting. Hoe vroege darmkanker te vinden 15

Dr. C. Richard Boland, MD, explains how microRNA biomarkers in blood and fecal samples offer a promising non-invasive method for early colon cancer detection. He...

"Kankerfamilie: de zoektocht naar de oorzaak van erfelijke darmkanker". Boek van Dr. C. Richard Boland. 16

17. "Kankerfamilie: de zoektocht naar de oorzaak van erfelijke darmkanker". Boek van Dr. C. Richard Boland. 16

Dr. C. Richard Boland, MD, shares his personal journey uncovering the genetic cause of Lynch syndrome in his family. His book details how early-onset colon...