Prognosis in Stage 4 metastatic colon cancer. 10-year survival for 30% of patients. 6

Prognosis in Stage 4 metastatic colon cancer. 10-year survival for 30% of patients. 6

Prognosis in Stage 4 metastatic colon cancer. 10-year survival for 30% of patients. 6

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“Five-year survival of stage 4 colon cancer patients whose liver metastases convert to resection is 50% now. 25% of stage 4 colon cancer patients with resectable liver metastases are disease-free at 5 years. 10-year survival for stage 4 colon cancer patients in whom we can resect liver metastases is now approaching 30%.” “I have 20-year survivors from stage 4 metastatic colon cancer now.” Metastatic stage 4 colon cancer prognosis update. Dr. Anton Titov, MD. Colorectal cancer liver metastases prognosis. Survival rate has improved dramatically. Dr. Graeme Poston, MD. Advanced stage 4 colon cancer surgery for liver metastases improves survival rate and long-term prognosis. Video interview with leading British liver cancer surgeon specializing in colorectal cancer metastases resection. Dr. Anton Titov, MD. Medical second opinion confirms that liver metastatic stage 4 colorectal cancer diagnosis is correct and complete. Medical second opinion also confirms that liver metastases surgery is possible in stage 4 colon cancer to improve prognosis. Dr. Graeme Poston, MD. Best treatment for advanced stage 4 colon cancer with liver metastatic lesions increases 5-year survival and many patients are cured. Medical second opinion helps to choose the best treatment for stage 4 colorectal cancer with liver metastases: 10-year prognosis is improving. Get medical second opinion on advanced colorectal cancer and be confident that your prognosis is the best. Best colorectal cancer treatment center for liver metastases. Dr. Graeme Poston, MD. Video interview with leading expert in colorectal cancer liver metastases treatment surgery. Metastatic stage 4 colon cancer prognosis update. Dr. Anton Titov, MD. Metastatic stage 4 colorectal cancer is now treated by combination chemotherapy and extensive surgical treatment. Often there is multi-stage surgical treatment of advanced colon cancer. What are the overall expectations for survival of patients with metastatic colorectal cancer? Dr. Anton Titov, MD. What is prognosis? Sometimes liver metastases are present in colon cancer? Dr. Graeme Poston, MD. Leading liver cancer surgeon. Sometimes the patient has completely unresectable liver metastases from colorectal cancer. Such stage 4 colon cancer patient with liver metastases might never convert to resectable liver lesions. But we are still looking at median survival now in excess of 30 months. Dr. Graeme Poston, MD. If patients are fit enough to receive treatment for stage 4 metastatic colon cancer. For those colon cancer patients that have resectable liver metastases upfront. Or for those stage 4 colon cancer patients whose liver metastases convert to resection. Five-year survival of such patients is 50% now. Half of those who survive 5 years. Or 25% of stage 4 colon cancer patients with resectable liver metastases are disease-free at 5 years. 10-year survival for stage 4 colon cancer patients in whom we can resect liver metastases is now approaching 30%. Dr. Graeme Poston, MD. Leading liver cancer surgeon. Patients with stage 4 colorectal cancer live longer after liver metastases resection. The chance of cancer recurrence diminishes. Dr. Anton Titov, MD. After treatment for stage 4 colorectal cancer with liver metastases, patient can survive. If the patient is disease-free at 10 years, this patient is cured from cancer. Dr. Graeme Poston, MD. We know from survival data from Memorial Hospital in New York. When the patient gets to 10 years disease-free survival from metastatic colorectal cancer. The survival line is flat out to 20 years. Dr. Anton Titov, MD. It is possible to have a 10-year survival in a significant percentage of patients? Dr. Anton Titov, MD. Even with the liver metastatic disease in stage 4 colorectal cancer? Dr. Graeme Poston, MD. Leading liver cancer surgeon. I have 20-year survivors from metastatic stage 4 colorectal cancer with liver metastases resected. They die of old age. But I have now have got 20-year survivors from metastatic colon cancer. Dr. Anton Titov, MD. That is an amazing progress of metastatic colon cancer treatment. This underscores the value of multimodality therapies for colon cancer. Dr. Graeme Poston, MD. Leading liver cancer surgeon. Yeah, absolutely, absolutely. That is the key to metastatic colon cancer treatment and improved prognosis. It is multimodal therapy. It is absolutely essential that metastatic colon cancer patients are managed by multidisciplinary teams that can work together. In my group we have not just the medical oncologist and radiation oncologist. Dr. Graeme Poston, MD. But we have the liver surgeon, the colorectal surgeon, and the chest surgeon. They are all in the same room at the same time discussing colon cancer patient's treatment options. We are frequently looking at patients who present in stage 4 rectal cancer with a big rectal tumor and several liver metastases. They possibly have two or three lung metastases. Dr. Graeme Poston, MD. We have to work out a stage 4 colorectal cancer treatment strategy for the next 12 months for that patient. Because oftentimes, these metastatic colorectal cancer patients will need a long course of neoadjuvant chemotherapy for the primary tumor in the rectum. In the interim we should treat colorectal cancer metastases in the liver and in the lungs. Surgical operation on a liver happens whilst they are receiving the neoadjuvant chemotherapy. It may well be the following. Dr. Anton Titov, MD. Stage 4 colorectal cancer patients get first chemotherapy and then liver metastases resection. The last treatment is the primary tumor being removed. in the meantime, they have had the liver metastases removed and the lung metastases removed. Patient had a long course of neoadjuvant radiotherapy with chemotherapy. Dr. Graeme Poston, MD. Leading liver cancer surgeon. You have to tell that metastatic stage 4 colon cancer patient. "It is going to be hard work for the next 12 months." "You are going to have probably three surgical operations. You are going to have a lot of radiation and systemic colon cancer chemotherapy." But hopefully this time next year, you will be disease-free from stage 4 metastatic colorectal cancer. Dr. Anton Titov, MD. The primary colorectal cancer tumor will be removed at the last stage. Dr. Graeme Poston, MD. Leading liver cancer surgeon. Primary colorectal cancer tumor may be the last thing to come out, yes. Dr. Anton Titov, MD. That is very impressive progress in metastatic stage 4 colorectal cancer treatment. Especially when liver metastases or lung metastases are present. Dr. Graeme Poston, MD. Stage 4 metastatic colon cancer prognosis update: 20-year survival after liver metastases resection is possible. Choose leading surgeon and chemotherapy protocols wisely.

For a surgeon, knowledge is more important than experience. Leading cancer surgeon.
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