1. Dr. Matt Kaeberlein. Anti-aging, Longevity Expert. Biography. 0
Dr. Matt Kaeberlein, MD, PhD, explains the mechanisms of aging and the promotion of healthspan. He details his extensive research background and prestigious awards in...
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2. Diets and Aging: Promise and reality. 1
Dr. Matt Kaeberlein, MD, PhD, explains how diet profoundly impacts the biological aging process. He details the proven effects of caloric restriction in animal models....
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3. Risks of caloric restriction to slow aging. Risks of diets for immune system. 2
Dr. Matt Kaeberlein, MD, PhD, explains the potential risks of long-term caloric restriction. He discusses the unproven benefits of severe dieting for human lifespan extension....
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4. Intermittent fasting is a dirty drug. Is it all about caloric restriction? 3
Dr. Matt Kaeberlein, MD, explains how caloric restriction and intermittent fasting impact healthspan. He discusses the potential benefits of these dietary interventions for biological aging....
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5. Dogs and anti-aging research. There are 4 species of dogs. Why neutered dogs live longer? 8
Dr. Matt Kaeberlein, MD, PhD, explains how neutering impacts canine longevity and disease. He discusses the Dog Aging Project's longitudinal study.
Dr. Matt Kaeberlein, MD, explains the four major fictions of anti-aging diets. He clarifies that caloric restriction does not always extend lifespan. Genetic background plays...
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7. Male vs. female differences in response to anti-aging diet. Sex and caloric restriction. 5
Dr. Matt Kaeberlein, MD, PhD, explains how sex differences impact responses to anti-aging diets. He discusses the variable effects of caloric restriction in male versus...
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8. How to study longevity? Companion dogs. Methods of anti-aging research. 6
Dr. Matt Kaeberlein, MD, PhD, explains modern methods of anti-aging research. He details the use of various model organisms from yeast to mice.
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9. General Stanley McChrystal and once-a-day eating habit. Healthy or not? 7
Dr. Matt Kaeberlein, MD, PhD, explains the potential health impacts of once-a-day eating. He discusses the correlation between time-restricted feeding and weight management.
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10. Rapamycin is not a miracle drug for aging. Rapamycin and mTOR in psychiatry. 9
Dr. Matt Kaeberlein, MD, PhD, explains the central role of the mTOR pathway in health and disease. He details how mTOR acts as a nutrient-sensing...
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11. Rapamycin in Alzheimer’s disease. Reputational issues in use of rapamycin. 10
Dr. Anton Titov, MD, explores these critical issues in depth.
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12. Rapamycin side effects vs. Alzheimer’s disease decline. Important disclaimer. 11
Dr. Matt Kaeberlein, MD, PhD, explains a new study analyzing off-label rapamycin use for Alzheimer's disease. He details a survey-based research project capturing patient experiences...
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13. Rapamycin for slowing of aging. What dose? What is typical schedule for rapamycin? 12
Dr. Matt Kaeberlein, MD, PhD, explains the differences in rapamycin dosing for organ transplant versus potential anti-aging applications. He details the typical once-weekly 4-6 mg...
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14. Future in anti-aging research. Stem cells and Epigenetic reprogramming. 13
Dr. Matt Kaeberlein, MD, PhD, explains the future of anti-aging research. He discusses the continued importance of rapamycin and metformin studies.
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15. Fund anti-aging research better rather than do endless ‘wars on cancer’. 14
Dr. Matt Kaeberlein, MD, PhD, explains how biological aging is the primary risk factor for major diseases. He advocates for a fundamental shift in biomedical...
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