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Brain Tumor Diagnosis.
Alzheimer's & Prion Diseases.

Dr. Sebastian Brandner
ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ. ืžื•ืžื—ื” ืœื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื” ืฉืœ ื’ื™ื“ื•ืœื™ ืžื•ื—. ื‘ื™ื•ื’ืจืคื™ื”. 0
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1. ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ. ืžื•ืžื—ื” ืœื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื” ืฉืœ ื’ื™ื“ื•ืœื™ ืžื•ื—. ื‘ื™ื•ื’ืจืคื™ื”. 0

ืžื•ืžื—ื” ืžื•ื‘ื™ืœื” ื‘ื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื” ืฉืœ ื’ื™ื“ื•ืœื™ ืžื•ื— ื•ืžื—ืœื•ืช ื ื•ื™ืจื•ื“ื’ื ืจื˜ื™ื‘ื™ื•ืช, ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD, ืžืกื‘ื™ืจ ื›ื™ืฆื“ ืื‘ื—ื•ืŸ ืžื•ืœืงื•ืœืจื™ ืžื—ื•ืœืœ ืžื”ืคื›ื” ื‘ืกื™ื•ื•ื’ ื’ื™ื“ื•ืœื™ ืžื•ื—. ื™ื•"ืจ ื”ื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื” ื‘ืื•ื ื™ื‘ืจืกื™ื˜ืช ืงื•ืœื’'...

ื›ื™ืฆื“ ืœืื‘ื—ืŸ ืืช ืกื•ื’ ื”ื’ื™ื“ื•ืœ ื”ืžื•ื—ื™? ืžื•ืžื—ื” ืœื ื•ื™ืจื•-ืื•ื ืงื•ืœื•ื’ื™ื” ืžืกื‘ื™ืจ. ื—ืœืง 1.
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2. ื›ื™ืฆื“ ืœืื‘ื—ืŸ ืืช ืกื•ื’ ื”ื’ื™ื“ื•ืœ ื”ืžื•ื—ื™? ืžื•ืžื—ื” ืœื ื•ื™ืจื•-ืื•ื ืงื•ืœื•ื’ื™ื” ืžืกื‘ื™ืจ. ื—ืœืง 1.

ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื”, ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD, ืžืกื‘ื™ืจ ืืช ื”ืชื”ืœื™ืš ื”ืฉืœื‘ื™ ืฉืœ ืื‘ื—ื•ืŸ ืกื•ื’ื™ ื’ื™ื“ื•ืœื™ ืžื•ื—, ื”ื—ืœ ืžื‘ื“ื™ืงืช ืจืงืžื” ืจืืฉื•ื ื™ืช ื•ืขื“ ืœื‘ื“ื™ืงื•ืช ืžื•ืœืงื•ืœืจื™ื•ืช ืžืชืงื“ืžื•ืช. ื”ืžืกืข...

ืื™ืš ืžืื‘ื—ื ื™ื ืกื•ื’ ื’ื™ื“ื•ืœ ืžื•ื—ื™? ืžื•ืžื—ื” ืœื ื•ื™ืจื•-ืื•ื ืงื•ืœื•ื’ื™ื” ืžืกื‘ื™ืจ. ื—ืœืง 2. 2
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3. ืื™ืš ืžืื‘ื—ื ื™ื ืกื•ื’ ื’ื™ื“ื•ืœ ืžื•ื—ื™? ืžื•ืžื—ื” ืœื ื•ื™ืจื•-ืื•ื ืงื•ืœื•ื’ื™ื” ืžืกื‘ื™ืจ. ื—ืœืง 2. 2

ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื”, ืžืกื‘ื™ืจ ื›ื™ืฆื“ ืฆื•ื•ืชื™ื ืจื‘-ืžืงืฆื•ืขื™ื™ื ืžืฉืœื‘ื™ื ืื‘ื—ื•ืŸ ืžื•ืœืงื•ืœืจื™, ื”ื“ืžื™ื” ื•ืžื•ืžื—ื™ื•ืช ืงืœื™ื ื™ืช ื›ื“ื™ ืœืื‘ื—ืŸ ื‘ืžื“ื•ื™ืง ืกื•ื’ื™ ื’ื™ื“ื•ืœื™ ืžื•ื— ื•ืœื™ืฆื•ืจ ืชื•ื›ื ื™ื•ืช ื˜ื™ืคื•ืœ...

ื’ื™ื“ื•ืœื™ ืžื•ื— ืžืื•ื‘ื—ื ื™ื ื‘ืชื“ื™ืจื•ืช ื’ื‘ื•ื”ื” ื™ื•ืชืจ ื›ื™ื•ื? 3
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4. ื’ื™ื“ื•ืœื™ ืžื•ื— ืžืื•ื‘ื—ื ื™ื ื‘ืชื“ื™ืจื•ืช ื’ื‘ื•ื”ื” ื™ื•ืชืจ ื›ื™ื•ื? 3

ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื” ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD, ื‘ื•ื—ืŸ ืžื“ื•ืข ื”ืื‘ื—ื•ื ื™ื ืฉืœ ื’ื™ื“ื•ืœื™ ืžื•ื— ืขืœื• ื‘ื›-25% ื‘ืžื”ืœืš 25 ื”ืฉื ื™ื ื”ืื—ืจื•ื ื•ืช, ื•ื—ื•ืงืจ ื”ืื ืžื“ื•ื‘ืจ ื‘ืขืœื™ื™ื” ืืžื™ืชื™ืช ื‘ืฉื›ื™ื—ื•ืช...

ืืกื˜ืจื•ืฆื™ื˜ื•ืžื” ืื• ืื•ืœื™ื’ื•ื“ื ื“ืจื•ื’ืœื™ื•ืžื”? ืื‘ื—ื•ืŸ ืžื“ื•ื™ืง ืฉืœ ื’ื™ื“ื•ืœื™ ืžื•ื—. 4
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5. ืืกื˜ืจื•ืฆื™ื˜ื•ืžื” ืื• ืื•ืœื™ื’ื•ื“ื ื“ืจื•ื’ืœื™ื•ืžื”? ืื‘ื—ื•ืŸ ืžื“ื•ื™ืง ืฉืœ ื’ื™ื“ื•ืœื™ ืžื•ื—. 4

ื’ื™ืœื•ื™ ื”ืคืจื™ืฆื” ืฉืœ ืฉื ื•ืช ื”-90 ืขืœ ื™ื“ื™ ื“"ืจ ืงื™ื™ืจื ืงืจื•ืก ื–ื™ื”ื” ืื•ื‘ื“ืŸ ืกื™ืžื•ืœื˜ื ื™ ืฉืœ ื–ืจื•ืขื•ืช ื›ืจื•ืžื•ื–ื•ื 1p ื•-19q ื›ืกื™ืžืŸ ื”ื™ื›ืจ ืฉืœ ืื•ืœื™ื’ื•ื“ื ื“ืจื•ื’ืœื™ื•ืžื”. ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD,...

ื’ืœื™ื•ื‘ืœืกื˜ื•ืžื” ืžื•ืœื˜ื™ืคื•ืจืžื” (GBM). ืื‘ื—ื•ืŸ ืžื•ืœืงื•ืœืจื™ ืžื“ื•ื™ืง. 5
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6. ื’ืœื™ื•ื‘ืœืกื˜ื•ืžื” ืžื•ืœื˜ื™ืคื•ืจืžื” (GBM). ืื‘ื—ื•ืŸ ืžื•ืœืงื•ืœืจื™ ืžื“ื•ื™ืง. 5

ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื”, ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD, ืžืกื‘ื™ืจ ื›ื™ืฆื“ ื‘ื“ื™ืงื” ืžื•ืœืงื•ืœืจื™ืช ืœืžืชื™ืœืฆื™ื” ืฉืœ ืžืงื“ื MGMT ืžืฉืคืจืช ืืช ื”ืื‘ื—ื•ืŸ ื•ื”ื˜ื™ืคื•ืœ ื‘ื’ืœื™ื•ื‘ืœืกื˜ื•ืžื” ืžื•ืœื˜ื™ืคื•ืจืžื” (GBM). ื”ื‘ื“ื™ืงื” ื”ืืคื™ื’ื ื˜ื™ืช ืžื ื‘ืืช...

ืื‘ื—ื•ืŸ ืžื“ื•ื™ืง ืฉืœ ื’ื™ื“ื•ืœื™ ืžื•ื—. ืžื ื™ื ื’ื™ื•ืžื”, ืืกื˜ืจื•ืฆื™ื˜ื•ืžื”, ื’ืœื™ื•ื‘ืœืกื˜ื•ืžื”. 6
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7. ืื‘ื—ื•ืŸ ืžื“ื•ื™ืง ืฉืœ ื’ื™ื“ื•ืœื™ ืžื•ื—. ืžื ื™ื ื’ื™ื•ืžื”, ืืกื˜ืจื•ืฆื™ื˜ื•ืžื”, ื’ืœื™ื•ื‘ืœืกื˜ื•ืžื”. 6

ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื”, ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD, ืžืกื‘ื™ืจ ื›ื™ืฆื“ ืื‘ื—ื•ืŸ ืžื•ืœืงื•ืœืจื™ ืžื—ื•ืœืœ ืžื”ืคื›ื” ื‘ืื‘ื—ื•ืŸ ื•ื‘ื˜ื™ืคื•ืœ ื‘ื’ื™ื“ื•ืœื™ ืžื•ื—. ื”ื•ื ืžืคืจื˜ ืืช ื”ืชืคืงื™ื“ ื”ืงืจื™ื˜ื™ ืฉืœ ื‘ื“ื™ืงืช ืžื•ื˜ืฆื™ื™ืช...

"ื˜ื‘ื™ืขืช ืืฆื‘ืข ืฉืœ ื’ื™ื“ื•ืœื™ ืžื•ื—". ืื‘ื—ื•ืŸ ืžื•ืœืงื•ืœืจื™ ืฉืœ ืกืจื˜ืŸ ื”ืžื•ื—. 7
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8. "ื˜ื‘ื™ืขืช ืืฆื‘ืข ืฉืœ ื’ื™ื“ื•ืœื™ ืžื•ื—". ืื‘ื—ื•ืŸ ืžื•ืœืงื•ืœืจื™ ืฉืœ ืกืจื˜ืŸ ื”ืžื•ื—. 7

ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื”, ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD, ืžืกื‘ื™ืจ ื›ื™ืฆื“ ืื‘ื—ื•ื ื™ื ืžื•ืœืงื•ืœืจื™ื™ื ืžืชืงื“ืžื™ื ื›ืžื• ืคืจื•ืคื™ืœ ืžืชื™ืœืฆื™ื” ื•ื ื™ืชื•ื— ื›ืจื•ืžื•ื–ื•ืžืœื™ ื™ื•ืฆืจื™ื "ื˜ื‘ื™ืขื•ืช ืืฆื‘ืข" ืžื“ื•ื™ืงื•ืช ืœืื‘ื—ื•ืŸ ื’ื™ื“ื•ืœื™ ืžื•ื—, ื•ืžืืคืฉืจื™ื...

โ€˜ื’ืœื™ื•ื‘ืœืกื˜ื•ืžื” ื‘ื”ืชื”ื•ื•ืชโ€™ ื‘ื“ื™ืงื•ืช ื’ื ื˜ื™ื•ืช ืžื ื‘ืื•ืช ืคืจื•ื’ื ื•ื–ื” ืฉืœ ื’ื™ื“ื•ืœ ืžื•ื—ื™. ืžืงืจื” ืงืœื™ื ื™. 8
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9. โ€˜ื’ืœื™ื•ื‘ืœืกื˜ื•ืžื” ื‘ื”ืชื”ื•ื•ืชโ€™ ื‘ื“ื™ืงื•ืช ื’ื ื˜ื™ื•ืช ืžื ื‘ืื•ืช ืคืจื•ื’ื ื•ื–ื” ืฉืœ ื’ื™ื“ื•ืœ ืžื•ื—ื™. ืžืงืจื” ืงืœื™ื ื™. 8

ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื” ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD, ืžืกื‘ื™ืจ ื›ื™ืฆื“ ื‘ื“ื™ืงื•ืช ื’ื ื˜ื™ื•ืช ืžืชืงื“ืžื•ืช ืžืืชืจื•ืช ื’ืœื™ื•ื‘ืœืกื˜ื•ืžื” ื‘ืฉืœื‘ ืžื•ืงื“ื ื›ืืฉืจ ื”ืคืชื•ืœื•ื’ื™ื” ื”ืžืกื•ืจืชื™ืช ื ืจืื™ืช ืฉืคื™ืจื”, ื•ืžืืคืฉืจื•ืช ื˜ื™ืคื•ืœ ืื’ืจืกื™ื‘ื™ ืžื•ืงื“ื...

ื’ื™ื“ื•ืœื™ ืžื•ื— ื•ืชืื™ ื’ื–ืข. ื›ื™ืฆื“ ืชืื™ ื’ื–ืข ื”ื•ืคื›ื™ื ืœืกืจื˜ืŸ ื”ืžื•ื—. 9
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10. ื’ื™ื“ื•ืœื™ ืžื•ื— ื•ืชืื™ ื’ื–ืข. ื›ื™ืฆื“ ืชืื™ ื’ื–ืข ื”ื•ืคื›ื™ื ืœืกืจื˜ืŸ ื”ืžื•ื—. 9

ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื” ื•ื‘ื—ืงืจ ื’ื™ื“ื•ืœื™ ืžื•ื—, ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD, ืžืกื‘ื™ืจ ื›ื™ืฆื“ ืชืื™ ื’ื–ืข ืžื•ื—ื™ื™ื ื™ื›ื•ืœื™ื ืœื”ืคื•ืš ืœื’ื™ื“ื•ืœื™ ืžื•ื— ืื’ืจืกื™ื‘ื™ื™ื ื›ืžื• ื’ืœื™ื•ื‘ืœืกื˜ื•ืžื” ืžื•ืœื˜ื™ืคื•ืจืžื” (GBM). ื”ื•ื...

ื”ืื ื ื™ืชืŸ ืœื”ืขื‘ื™ืจ ื“ืžื ืฆื™ื”? ืžื—ืœืช ืืœืฆื”ื™ื™ืžืจ ื•ืžื—ืœืช ืงืจื•ื™ืฆืคืœื“-ื™ืขืงื‘. ื—ืœืง 1. 10
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11. ื”ืื ื ื™ืชืŸ ืœื”ืขื‘ื™ืจ ื“ืžื ืฆื™ื”? ืžื—ืœืช ืืœืฆื”ื™ื™ืžืจ ื•ืžื—ืœืช ืงืจื•ื™ืฆืคืœื“-ื™ืขืงื‘. ื—ืœืง 1. 10

ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ืžื—ืœื•ืช ื ื™ื•ื•ื ื™ื•ืช ืฉืœ ืžืขืจื›ืช ื”ืขืฆื‘ื™ื, ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD, ืžืกื‘ื™ืจ ื›ื™ืฆื“ ืžื—ืœืช ืงืจื•ื™ืฆืคืœื“-ื™ืขืงื•ื‘ (CJD) ื—ื•ืœืงืช ืžื ื’ื ื•ื ื™ ืงื™ืคื•ืœ ื—ืœื‘ื•ืŸ ืœืงื•ื™ ืขื ืืœืฆื”ื™ื™ืžืจ ื•ืคืจืงื™ื ืกื•ืŸ, ื‘ืขื•ื“...

ื”ืื ืžื—ืœืช ืืœืฆื”ื™ื™ืžืจ ืื™ื ื” ื ื™ืชื ืช ืœื”ืขื‘ืจื”? ืืš ื“ืžื ืฆื™ื” ืขืงื‘ ืื ื’ื™ื•ืคืชื™ื” ืขืžื™ืœื•ืื™ื“ื™ืช ืžื•ื—ื™ืช ื ื™ืชื ืช ืœื”ืขื‘ืจื”. ื—ืœืง 2. 11
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12. ื”ืื ืžื—ืœืช ืืœืฆื”ื™ื™ืžืจ ืื™ื ื” ื ื™ืชื ืช ืœื”ืขื‘ืจื”? ืืš ื“ืžื ืฆื™ื” ืขืงื‘ ืื ื’ื™ื•ืคืชื™ื” ืขืžื™ืœื•ืื™ื“ื™ืช ืžื•ื—ื™ืช ื ื™ืชื ืช ืœื”ืขื‘ืจื”. ื—ืœืง 2. 11

ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ืžื—ืœื•ืช ื ื™ื•ื•ื ื™ื•ืช ืฉืœ ืžืขืจื›ืช ื”ืขืฆื‘ื™ื, ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD, ืžืกื‘ื™ืจ ื›ื™ืฆื“ ื—ืœื‘ื•ื ื™ื ืžืกื•ื™ืžื™ื ื”ื’ื•ืจืžื™ื ืœื“ืžื ืฆื™ื” ื™ื›ื•ืœื™ื ืœืขื‘ื•ืจ ื‘ืืžืฆืขื•ืช ื”ืœื™ื›ื™ื ืจืคื•ืื™ื™ื. ื‘ืขื•ื“ ืฉืžื—ืœืช ืืœืฆื”ื™ื™ืžืจ...

ืžื—ืœืช ืืœืฆื”ื™ื™ืžืจ ื•ืžื—ืœืช ืงืจื•ื™ืฆืคืœื“-ื™ืขืงื‘. ื‘ืžื” ื”ืŸ ื“ื•ืžื•ืช? 12
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13. ืžื—ืœืช ืืœืฆื”ื™ื™ืžืจ ื•ืžื—ืœืช ืงืจื•ื™ืฆืคืœื“-ื™ืขืงื‘. ื‘ืžื” ื”ืŸ ื“ื•ืžื•ืช? 12

ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ืžื—ืœื•ืช ื ื™ื•ื•ื ื™ื•ืช ืฉืœ ืžืขืจื›ืช ื”ืขืฆื‘ื™ื, ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD, ืžืกื‘ื™ืจ ืืช ื”ื“ืžื™ื•ืŸ ื”ืžืคืชื™ืข ื‘ื™ืŸ ืžื—ืœืช ืืœืฆื”ื™ื™ืžืจ ืœืžื—ืœืช ืงืจื•ื™ืฆืคืœื“-ื™ืขืงื•ื‘ (CJD), ื›ื•ืœืœ ื”ืชืคืชื—ื•ืชืŸ ื”ืกืคื•ื ื˜ื ื™ืช ื‘-95%...

ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ืื‘ื—ื•ืŸ ื’ื™ื“ื•ืœื™ ืžื•ื—. ืžื” ืžื ื™ืข ืื•ืชื• ื‘ืขื‘ื•ื“ื” ื•ื‘ื—ื™ื™ื? 13
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14. ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ืื‘ื—ื•ืŸ ื’ื™ื“ื•ืœื™ ืžื•ื—. ืžื” ืžื ื™ืข ืื•ืชื• ื‘ืขื‘ื•ื“ื” ื•ื‘ื—ื™ื™ื? 13

ืžื•ืžื—ื” ืžื•ื‘ื™ืœ ื‘ื ื•ื™ืจื•ืคืชื•ืœื•ื’ื™ื”, ื“"ืจ ืกื‘ืกื˜ื™ืืŸ ื‘ืจื ื“ื ืจ, MD, ืžืกื‘ื™ืจ ื›ื™ืฆื“ ืžืงืจื™ื ืžื•ืจื›ื‘ื™ื ืฉืœ ื’ื™ื“ื•ืœื™ ืžื•ื— ื•ืืชื’ืจื™ื ืื‘ื—ื•ื ื™ื™ื ื‘ืœืชื™ ืคืชื•ืจื™ื ืžื ื™ืขื™ื ืืช ืขื‘ื•ื“ืชื• ื”ืงืœื™ื ื™ืช ื•ื”ืžื—ืงืจื™ืช ื‘ืžืจื›ื– ืจืคื•ืื™...

ืฉืคืจ ืืช ืชื•ื›ื ื™ืช ื”ื˜ื™ืคื•ืœ ืฉืœืš ืขื ืคืื ืœ ืฉืœ ืจื•ืคืื™ื ืžื•ื‘ื™ืœื™ื ืฉืžืชืื™ืžื™ื ื‘ื“ื™ื•ืง ืœืžืงืจื” ืฉืœืš.

ืฉืคืจ ืืช ืชื•ื›ื ื™ืช ื”ื˜ื™ืคื•ืœ ืฉืœืš ืขื ืคืื ืœ ืฉืœ ืจื•ืคืื™ื ืžื•ื‘ื™ืœื™ื ืฉืžืชืื™ืžื™ื ื‘ื“ื™ื•ืง ืœืžืงืจื” ืฉืœืš.

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