Let’s talk about also Alzheimer's disease. There is a genetic influence. But it can also arise spontaneously. Dr. Anton Titov, MD. The vast majority, 95% of of Alzheimer’s disease cases are spontaneous. 95% Creutzfeldt-Jakob disease (CJD) cases are spontaneous. But once disease happens, it can be transmitted via the biological material. Yes, that's correct! Dr. Sebastian Brandner, MD. I would say very clearly, Alzheimer’s disease and Creutzfeldt-Jakob disease could be transmitted via medical procedures. Procedures where brain tissue is transmitted in some way. We don't yet know how risky that is. We don’t know how common that is. Whether it's easy or difficult. We should also say. It’s not that we can transmit Alzheimer's disease. We can transmit the protein that then deposits and amplifies in the recipient brain. It was established that this protein can cause some problems in the blood vessels. Blood vessels in the brain become more brittle. They start bleeding. We have seen a few examples. The transmission without prion disease was also possible. Dr. Sebastian Brandner, MD. That leads young patients to the potential development of these vascular problems. It is like Alzheimer’s disease. We call it cerebral amyloid angiopathy. This is a whole different concept of disease. Yes, that's correct! It's amazing, these diseases are not bacterial and not viral. Alzheimer’s disease and Creutzfeldt-Jakob disease are caused by a protein. Dr. Anton Titov, MD. It can precipitate intrinsic changes in the brain.