Transcript of video
Chronic liver disease treatment focuses on simple but important steps. Leading expert in liver diseases describes how to best prevent and treat chronic liver diseases. Steatohepatitis and autoimmune liver disease. How to stop chronic liver disease deterioration to cirrhosis and liver cancer? Chronic liver disease treatment is improving. Dr. Anton Titov, MD. Video interview with leading expert in liver diseases. Dr. Simon Robson, MD. Nonalcoholic fatty liver disease treatment is based on early diagnosis. Chronic liver disease treatment is important to start as early as possible. Steatohepatitis is an early sign of fatty liver disease. Medical second opinion helps to make sure diagnosis of chronic liver disease is correct and complete. Medical second opinion also helps to choose the best treatment for chronic liver disease and viral hepatitis. Dr. Anton Titov, MD. Medical second opinion in autoimmune liver disease and rheumatological liver disorder. Iron storage (hemochromatosis) and copper storage (Wilson’s disease) liver diseases increase in frequency. Dr. Simon Robson, MD. Chronic liver disease treatment is focused on lifestyle change and food habit changes to avoid further damage to liver. It is important to recognize and treat autoimmune liver disease as early as possible. Late diagnosis of autoimmune liver disease leads to liver cirrhosis and liver failure. Chronic liver disease treatment is based on early diagnosis and dietary modifications. Treatment of chronic liver disease. Dr. Simon Robson, MD. Harvard Medical School. We have potential cure for hepatitis B and hepatitis C. End-stage liver disease and liver cancer from viral hepatitis is going to decrease. Dr. Anton Titov, MD. What are the other major liver diseases that will be prominent in the future? Dr. Simon Robson, MD. Diabetes, obesity and nonalcoholic fatty liver disease is a major epidemic that we are going to see. Nonalcoholic fatty liver disease can progress to inflammation. We then call it steatohepatitis. Steatohepatitis simply means “liver inflammation in the presence of fat”. Many patients with steatohepatitis can worsen. Patients can suddenly present with liver cirrhosis. Patients with nonalcoholic fatty liver disease and steatohepatitis also can first present with complications of cirrhosis. They can have liver cancer. Patients are predisposed to nonalcoholic fatty liver disease and steatohepatitis. Dr. Simon Robson, MD. They are usually morbidly obese. They often have diabetes. Such patients are often treated with medications to treat Type 2 diabetes. Patients take oral hypoglycemic medications. There is not much we can do to preclude the development of nonalcoholic fatty liver disease (NAFLD) and steatohepatitis. The best prevention is to address the fundamental metabolic problems this lead to NAFLD and steatohepatitis. Other major form of liver disease is autoimmune liver disease. It can present as liver manifestation of rheumatic disease (rheumatological liver disorder). Autoimmune liver disease can also present as inflammatory bowel disease or celiac disease. Early diagnosis of autoimmune liver disease is important. Because we could miss correct diagnosis. We could fail to treat the patient with immunosuppressive medications. Patients can progress to liver cirrhosis, liver failure and death. Dr. Simon Robson, MD. Liver transplantation is the only treatment at advanced stage of autoimmune liver disease. We still see liver inflammation associated with metabolic disorders. Alpha-1 antitrypsin deficiency is one example of liver inflammation disorder. We also see liver problems associated with iron storage (hemochromatosis) and copper storage (Wilson’s disease). We also see liver diseases that are caused by problems with glycogen storage (glycogen storage diseases). Glycogen is animal starch. Iron storage disease, Wilson disease, and glycogen storage diseases are much more rare. Nonalcoholic fatty liver disease and steatohepatitis are more common. Dr. Simon Robson, MD. I have spoken of viral hepatitis B and hepatitis C. Other forms of liver disease are increasing in frequency. Because we can now treat more effectively hepatitis C and hepatitis B. Nonalcoholic fatty liver disease, steatohepatitis and diabetes are increasing. Diabetes is also rising. Alcoholic liver disease is a problem in North America and Europe. Dr. Anton Titov, MD. Rates of alcoholism and alcohol usage are increasing dramatically. There are few effective therapies for alcoholism. Dr. Simon Robson, MD. There are minimal antidotes to prevent liver injury if patients continue to drink alcohol heavily. We will discuss alcohol liver disease later in the interview. We will discuss nutrition, toxins and liver disease. It is important that we immunize patients against Hepatitis B and Hepatitis A. We have vaccines against Hepatitis B and Hepatitis A. It is important to diagnose other liver diseases early, such as iron overload (hemochromatosis). Early diagnosis of copper storage disorders (Wilson’s disease, Wilson disease) is important. It is important to make early diagnosis of autoimmune liver disease associated with inflammatory bowel disease. Not only viruses cause hepatitis. Dr. Simon Robson, MD. Many other diseases cause liver inflammation. Many other disorders can damage the liver. Chronic liver disease treatment. Dr. Anton Titov, MD. Video interview with leading expert in liver diseases. Autoimmune liver disease, steatohepatitis, iron and copper storage disease.