# Herbal Skincare and Aging: How Plant Extracts May Help Your Skin This review examines how plant-derived compounds in skincare products may slow or reduce the visible signs of skin aging. The authors analyzed studies published between 2000 and 2025. The authors found that herbal extracts contain bioactive compounds such as polyphenols, flavonoids, and essential oils. These compounds provide moisturizing, barrier-repairing, antioxidant, sunscreen, and anti-inflammatory benefits. Combining herbal extracts with nano-formulations (tiny delivery particles) may improve both effectiveness and stability. The authors conclude that plant-based skincare, alongside a balanced diet and healthy lifestyle, can meaningfully support skin health as people age. # Herbal Skincare and Aging: How Plant Extracts May Help Your Skin ## Table of Contents - Key Points - Background: Why Skin Aging Matters - How This Review Was Conducted - How Herbal Extracts Moisturize the Skin - How Herbal Extracts Repair the Skin Barrier - Antioxidant Activity of Herbal Extracts - Antioxidant Flavonoid Pathways in Aging - Sunscreen and Pigmentation Effects - What This Means for Patients - Limitations of This Review - Practical Recommendations - Frequently Asked Questions - Source Information ## Key Points - Plant extracts like green tea, aloe, chamomile, Centella asiatica, and hyaluronic acid may moisturize, repair the skin barrier, and provide antioxidant protection. - Herbal extracts with photoprotective properties may supplement, but not replace, sunscreen, since UV radiation is a major driver of skin aging. - Combining herbal extracts with nano-formulations may improve effectiveness and stability, though more research is needed. - The review is not a clinical trial; many cited studies are laboratory cell studies, and specific dosages or durations are not provided. - A balanced diet and healthy lifestyle, along with consistent use of reputable products, are recommended to support skin health as people age. ## Background: Why Skin Aging Matters Aging is an unavoidable phase of life. It is a multifactorial transition process that involves biological changes. These changes include a progressive decline in physiological activity and an increased vulnerability to age-related disorders such as osteoporosis and Alzheimer's disease. Aging begins at the cellular level and continues throughout the lifespan, ultimately leading to death. The effects of aging appear across biological factors first, followed by psychological and social dimensions. This includes a marked reduction in immune competence, deterioration of musculoskeletal integrity, and sensory impairments. The aging process is driven by two types of factors. **Intrinsic factors** are genetic and metabolic. They include impaired collagen synthesis, mitochondrial decay, hormonal changes, and cell senescence (cells stopping their normal division). **Extrinsic factors** are related to lifestyle and environment. They include ultraviolet (UV) radiation, environmental pollution, unhealthy dietary practices, smoking, and psychological tension. Extrinsic aging is more simply known as **photoaging**. Extrinsic factors accelerate the production of reactive oxygen species (ROS, which are unstable molecules that damage cells) and thus oxidative stress. This leads to lipid peroxidation, protein crosslinking, and the production of advanced glycation end products (AGEs). All of these processes lead to visible signs of aging. These signs include wrinkles, pigmentation, dryness, and loss of elasticity of the skin. In ancient times, anti-aging treatments generally focused on the skin. The skin is the most outward organ of the body and shows the most affected result of aging. Nowadays, science has evolved, and clinicians use topical chemical agents and cosmetic treatments. These include chemical peeling, laser resurfacing, and microdermabrasion. Invasive treatments include botulinum toxin (Botox) injections and dermal fillers. These treatments are effective in providing immediate cosmetic results. However, they also have very severe limitations. These limitations include high price, potential side effects, and scarce long-term safety evidence. Potential side effects include skin redness, allergic contact dermatitis, and post-inflammatory hyperpigmentation. Additionally, many chemical-based skincare products contain synthetic additives and preservatives. These raise public health and environmental concerns. Awareness has shifted consumer interest toward safer, more sustainable solutions. These solutions provide long-term skin health benefits. In response to these concerns, the global anti-aging market has experienced rapid growth. It reached an estimated value of **$216 billion in 2021**. This growth is fueled by awareness and a growing global aging population. The traditional primary market has been middle-aged and older consumers. However, younger age groups are increasingly embracing pre-aging. These groups include Millennials (25–40 years) and Generation Z (under 25 years). Pre-aging consists of early and regular application of sunscreen, antioxidants, and lifestyle changes to retard the onset of visible signs of aging. Men are also increasingly taking part in skincare. This is a sign of changing gender norms and wider acceptance of male grooming routines. The need for natural, plant-derived, and "clean" skincare products is increasing. Consumers are looking for products that meet safety, sustainability, and ethical sourcing standards. Natural products, particularly those from medicinal plants, have been recognized as viable alternatives to artificial cosmetics in anti-aging treatments. These ingredients usually contain plant extracts, essential oils, vitamins (e.g., A, C, and E), and minerals. These have antioxidant, anti-inflammatory, and photoprotective activities. The drug efficacy of plant ingredients stems from their richness in bioactive compounds. These include flavonoids, phenolics, and terpenoids. These compounds can neutralize free radicals, induce collagen synthesis, and aid in epidermal barrier function. These compounds not only act against environmental insults. They also regulate intracellular signaling pathways that are implicated in skin repair and regeneration. For example, green tea polyphenols, grape resveratrol, and turmeric curcumin are extensively documented for their reactive oxygen species scavenging activity. They also inhibit matrix metalloproteinases. These are enzymes responsible for the degradation of collagen and elastin in the dermis. By the World Health Organization's account, more than **20,000 medicinal plant species** are used in **91 nations**. These represent an immense pool of botanical ingredients available for cosmetic use. Preparations based on herbal extracts are viewed as milder, more compatible with skin physiology, and generally less likely to cause adverse reactions than synthetic alternatives. Furthermore, blending herbal and chemical ingredients is being researched more and more. This blending aims to synergize the strengths of ancient and conventional systems. These hybrid products may improve product performance while satisfying consumer requirements for transparency and natural character. Advances in formulation science have further enhanced the stability and bioavailability of plant-derived materials in cosmetic products. These advances include nanoencapsulation, emulsification, and transdermal delivery systems. This review gives a comprehensive overview of plant-derived active ingredients used in anti-aging cosmetics. It discusses their functions in water retention, brightening of the skin, photoprotection, regeneration of the epidermis, and regulation of inflammation. The review also critically evaluates the strengths and shortcomings of natural cosmetics in relation to standard chemical products. It highlights the growing trend of incorporating herbal extracts into current chemical-based cosmetics. This trend aims to obtain a higher level of therapeutic effects. Finally, the review emphasizes the need for ongoing research into herbal extract standardization, safety, and clinical efficacy. ## How This Review Was Conducted The authors performed a systematic literature review. They used the PubMed and ScienceDirect databases. They thoroughly examined articles published between **2000 and 2025**. The review used key phrases including "skin aging," "herbal extracts," and "anti-aging cosmetics." The aim was to examine the potential of natural herbal extracts in anti-aging skincare formulations. The review focused on the bioactivity and safety of these extracts. This focus aligns with current consumer trends favoring natural, organic, and eco-friendly products. ## How Herbal Extracts Moisturize the Skin Moisturization serves as a first line of defense against skin aging. It helps maintain the skin's elasticity and appearance. It also strengthens the barrier against environmental stressors. The **stratum corneum** (SC) is the outermost layer of skin. It is a water-lipid membrane that protects the body from external factors. For the SC to function optimally, it must contain around **30% water**. This water supports desquamation (the natural shedding of skin cells) and serves as a critical barrier against infection. Natural moisturizing factors within the SC contribute to hydration and water retention. When the moisture levels in the skin go below **10%**, the skin typically becomes rough and dry. It can even scale finely. Moisturizers can help repair damaged SC. Water-soluble ingredients provide temporary hydration by diffusing into the epidermis. Fat-soluble ingredients form a barrier film over the skin's surface. This reduces transepidermal water loss (TEWL, water escaping through the skin). Additionally, lipids and other ingredients can interact with the epidermal lipids. This provides relief from the dryness of the skin. Plant extracts are rich in two types of moisturizing agents. Polysaccharides and glycosides contain hydroxyl groups that retain water through hydrogen bonding. Vegetable oils improve the barrier functions of the skin, stimulate SC regeneration, minimize water loss, and influence sebaceous gland activity. Most plant polysaccharides, like dextran, exhibit humectant properties. This is largely dependent on the content, glycosyl structure, and molecular weight of the polysaccharides. Polar carboxyl groups found in the structures can form hydrogen bonds with water molecules. This retains moisture in the stratum corneum even at low concentration levels. Acetylated mannan is the primary active component in *Aloe barbadensis miller* extract. It is commonly used in cosmetics for its wound-healing properties and ability to retain moisture. Alginate, obtained from brown algae, is used as an emulsifier as well as a moisturizer. Alginate absorbs ambient moisture and develops a protective structure. This decreases the loss of water from the skin through a great softening action on the skin. Other water-soluble plant polysaccharides exhibit excellent properties of water absorption. These include *Opuntia dillenii*, astragalus, *Pholiota nameko*, and *Dendrobium officinale*. Green tea contains two primary bioactive compounds highly prized for their uses in skincare. These are tea polyphenols (TPP) and tea polysaccharides (TPS). TPP reduces lipid peroxidation within cells by increasing glutathione peroxidase levels and neutralizing free radicals. This protects cells from oxidative damage. Additionally, TPP promotes cell proliferation, strengthens the skin barrier, accelerates wound healing, and improves fluid flow within skin tissue. By reducing intercellular viscosity, it enhances skin elasticity. All catechins are present in green tea. However, epigallocatechin-3-gallate (EGCG) is one of the most active. This is due to its potent free radical scavenging ability and its capacity to significantly inhibit the action of ROS. It has high antioxidant potency. Another key green tea constituent is proanthocyanidins. This is a hydrophilic polyphenolic polymer with phenolic hydroxyl groups. It enhances moisture retention in the stratum corneum. This leads to improved hydration and skin elasticity. This resulted in a moisturizing effect meant to enhance the hydration and elasticity of the skin. These compounds offer significant benefits in skincare formulations, particularly due to their antioxidant properties. Chamomile extract is rich in quercetin. It displays impressive effects on the skin. It improves moisture retention, promotes repair in the skin, and helps control sebum excretion while lowering irritability. Quercetin is profoundly involved in this process by stimulating tight junction proteins for stronger cell-to-cell adhesion. This strengthens the barrier function of the skin. This is useful in the regulation of water and minimizes dehydration as well as reactivity. Similarly, a high number of flavonoids are still displayed as some of the most effective moisturizers in cosmetic products. Examples include chrysanthemum, pear cactus, and bamboo. The deep moisturizing of these plant extracts gives wonderful hydration to the skin. *Centella asiatica* extract is another leading natural moisturizer. It boasts wound-healing and moisturizing properties. The pentacyclic triterpenoid saponins, more importantly asiaticoside, increase hydration of the skin. They are thus commonly applied in products like wipes and skincare creams and ointments to heal wounds and scars. Hyaluronic acid is also a significant source of hydration for skin. It is of high molecular weight and viscous. This enables it to retain a large amount of water for enhanced moisturization. This attribute makes hyaluronic acid the gold standard concerning the preservation of hydration and prevention of moisture loss in the cosmetic industry. Vegetable oils are commonly applied in creams, lotions, and conditioners in cosmetics that utilize unsaturated fatty acids. For example, wheat germ oil gives an armor layer on the skin. It assists in protecting the skin from moisture loss and promotes the regeneration of skin qualities. This makes it ideal for dry, rough-surfaced skin. Emollient softening *Cocos nucifera* oil increases aquaporin AQP3, filaggrin, and integrin expression. This enhances keratinocyte differentiation. More than that, seed extracts of *Hippophae rhamnoides* L. and *Rubus idaeus* are emollients. They maintain hydration on the skin through stratum corneum strength and cell structure protection. In addition to hydrating the skin, these plant-based emollients play a fundamental role in strengthening and supporting the skin. They have acquired a status that is considered vital in cosmetic formulations. ## How Herbal Extracts Repair the Skin Barrier Aging in humans and other organisms is marked by the gradual accumulation of advanced glycation end products (AGEs) in the body. Common AGEs found in the skin include pentosidine, carboxymethyl-lysine, carboxyethyl-lysine, methylglyoxal, glyoxal, fructose-lysine, and glucosepane. AGE receptors are primarily located in the epidermis and dermis. Significantly higher expression levels are observed in sun-exposed skin compared to areas shielded from sunlight. This suggests that UV exposure intensifies AGE accumulation. This accelerates skin aging through oxidative stress and glycation processes. The maintenance of healthy, intact skin is crucially dependent on the presence of a functioning skin barrier. When the barrier function is disrupted, there can be excessive water loss through the transepidermal route, sensitivities of the skin, and susceptibility to environmental aggressors. Over the years, there has been considerable interest in plant extract cosmetics that can restore and strengthen the barrier function of the skin. Plant extracts with high levels of bioactive compounds are potential candidates for replacing synthetic alternatives in natural skin care products. This appeals to consumers who seek softer, gentler products. Such examples include chamomile extract, which improves the skin barrier and reduces irritation, along with rehydrating the oil balance. Its constituents, in particular quercetin, aid in strengthening junction-binding proteins to improve cellular connections. This consequently improves barrier function. Another ingredient extremely active in botanicals is *Centella asiatica* extract. It features excellent wound-healing and regenerative properties. The main active compound of the extract, madecassoside, is used in the majority of cosmetic formulas. This is due to its ability to enhance skin regeneration and minimize scarring. It should feature in any product focusing on wound and scar treatment. Hyaluronic acid is naturally found in the skin and functions to retain moisture within it. Cosmetically, it retains water molecules in the matrix of the skin so that the integrity of the skin's barrier remains intact. Hydration keeps the skin moist and lifted, reduces dehydration, and improves the elasticity of the texture of the skin. Several vegetable oils have been found to play significant roles in barrier repair formulations. A large category of major botanical oils has a selective capacity to create an occlusive skin barrier, restore the amount of moisture, and promote regeneration of skin. This category includes wheat germ oil, coconut oil, sea buckthorn oil, and raspberry oil. Together, these oils fortify the stratum corneum, the outermost skin layer, against environmental stress. Plant extract cosmetics vow to heal and rejuvenate the skin barrier in general. They reveal a holistic approach to skincare based on taking advantage of the multiple benefits that natural botanicals are blessed with. These benefits include both functional and cosmetic improvements in skin health. ## Antioxidant Activity of Herbal Extracts Oxidation is one of the most natural metabolic processes that occur in the human body. It results in the creation of a massive amount of free radicals and reactive oxygen species. When the antioxidant defense system fails to scavenge such excess free radicals, oxidative stress emerges. Such an imbalance can further lead to several skin aging problems caused by ROS. These ROS include superoxide radicals, hydrogen peroxide, hydroxyl radicals, singlet oxygen, and nitric oxide. These biologically active species can cause DNA mutations, modify gene expressions, and degrade integral cellular constituents such as lipids and proteins. Furthermore, ROS activates degradative enzymes such as collagenase, elastase, superoxide dismutase (SOD1), and hyaluronidase. This facilitates the breakdown of extracellular matrix components. This promotes premature aging skin. In vitro, the phytochemical extract of *Centella asiatica* has exhibited potential antioxidant and inhibitory activities against some destructive enzymes. Among the naturally occurring antioxidants, polyphenols have been recognized as the most abundant and powerful free radical scavengers. This is because of their hydroxyl groups attached to their aromatic rings. They are mainly categorized into flavonoids, phenolic acids, stilbenes, tannins, and coumarins. Notably, proanthocyanidins are the antioxidant agents of highest activity throughout the plant kingdom. Hydroxytyrosol, resveratrol, curcumin, and rosemary extract possess significant antioxidant properties. These can shield skin cells from the oxidation of DNA, further preventing UV-induced mutagenesis. Of the compounds mentioned above, the resveratrol present in red wine is essentially valued for its anti-aging attribute. This makes it fit into most antioxidant-enriched cosmetic formulations. ## Antioxidant Flavonoid Pathways in Aging Flavonoids are naturally occurring phenolic substances found in fruits, vegetables, tea, and other plant foods. They are most popularly known as potent antioxidants with broad protective powers for cells and skin. The antioxidant action of flavonoids is primarily attributed to their ability to scavenge reactive oxygen species. They do this through the donation of hydrogen atoms or electrons from hydroxyl groups that are on the B-ring of their molecular structure. This stabilizes free radicals, such as hydroxyl and peroxyl radicals. This blocks oxidative damage to cellular components. Besides directly scavenging ROS, flavonoids suppress the generation of these toxic species. They do this by inhibiting the activity of crucial enzymes responsible for ROS production. These enzymes include xanthine oxidase, NADPH oxidase, and mitochondrial succinoxidase. Flavonoids like quercetin and luteolin are highly effective in inhibiting these enzymes. This prevents oxidative stress in various cellular locations. Another important mechanism is metal ion chelation. Catechol-containing flavonoids can chelate redox-active metals such as iron and copper. These metals act as catalysts in Fenton reactions that result in the formation of highly reactive hydroxyl radicals. Chelating these metals with flavonoids inhibits further oxidative damage. In addition to their direct antioxidant actions, flavonoids regulate cellular defense systems. They do this through the activation of signaling pathways, including the Nrf2-ARE pathway. Upon activation, Nrf2 moves to the nucleus and binds to the antioxidant response element (ARE). This leads to the induction of endogenous antioxidant enzymes like superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx). Hydroxy acids consist of alpha-hydroxy acids such as citric, glycolic, lactic, malic, tartaric, and amygdalic acids. They are applied as topical exfoliants and skin rejuvenators. The high penetration capability of these acids makes them easily absorbed in the stratum corneum. They provide stimulation to higher turnover of cells and break down the intercellular bonds. ## Sunscreen and Pigmentation Effects Photoaging is caused by increased exposure to UV radiation. Today, it is common for skincare companies to include UV-scattering and absorbing agents in their anti-aging cosmetic products. These act as a defense mechanism against damage from UV light. Conversely, UV light induces matrix metalloproteinases. These contain elastases that deconstruct collagen, fibronectin, and elastin out of the extracellular matrix. This accelerates skin aging. ## What This Means for Patients This review shows that many plant-derived compounds have real, measurable effects on the skin. These effects include moisturizing, barrier repair, antioxidant protection, and sun protection. For patients, this means that choosing skincare products containing herbal extracts may offer meaningful benefits. The specific compounds with documented benefits include: - **Green tea polyphenols (EGCG)** — reduce oxidative damage, strengthen the skin barrier, and improve elasticity - **Aloe barbadensis miller (acetylated mannan)** — retains moisture and supports wound healing - **Chamomile extract (quercetin)** — improves moisture retention, strengthens cell-to-cell connections, and controls sebum - **Centella asiatica (asiaticoside, madecassoside)** — increases hydration, enhances regeneration, and minimizes scarring - **Hyaluronic acid** — retains large amounts of water and is considered the gold standard for hydration - **Vegetable oils (wheat germ, coconut, sea buckthorn, raspberry)** — create a protective barrier and promote regeneration - **Resveratrol (from red wine)** — provides antioxidant protection against UV-induced damage - **Flavonoids (quercetin, luteolin)** — scavenge free radicals and activate the body's own antioxidant enzymes The review also highlights that combining herbal extracts with nano-formulations (tiny delivery particles) enhances the efficacy of skincare regimens while improving stability. This means patients may get better results from products that use advanced delivery technology. Importantly, the authors note that the integration of plant-based resources, when combined with a balanced diet and a healthy lifestyle, can significantly enhance holistic and effective anti-aging skincare. Skincare alone is not enough. ## Limitations of This Review This is a review article, not a clinical trial. It summarizes findings from other studies rather than presenting new experimental data. The authors did not conduct original laboratory or patient research. The review covers articles published between 2000 and 2025. This is a broad time range, and older studies may not reflect current formulation technologies. The authors used only two databases (PubMed and ScienceDirect), so some relevant studies may have been missed. Many of the studies cited are in vitro (laboratory cell studies) rather than clinical trials in human patients. Results from cell studies do not always translate to the same effects in living people. The review does not provide specific dosages, treatment durations, or statistical significance values for most of the findings. The authors emphasize the need for ongoing research into herbal extract standardization, safety, and clinical efficacy. This means that the evidence base for herbal anti-aging skincare is still developing. ## Practical Recommendations Based on this review, patients interested in herbal anti-aging skincare may consider the following steps: 1. **Look for products containing proven botanical ingredients.** Green tea extract, chamomile, Centella asiatica, aloe vera, and hyaluronic acid have documented moisturizing and barrier-repair benefits. 1. **Choose products with antioxidant-rich plant extracts.** Polyphenols, flavonoids, resveratrol, and curcumin can help protect skin cells from oxidative damage. 1. **Use sun protection.** UV radiation is a major driver of skin aging. Herbal extracts with photoprotective properties may supplement, but not replace, sunscreen. 1. **Consider nano-formulated products.** Nanoencapsulation and transdermal delivery systems may improve the stability and absorption of plant-derived ingredients. 1. **Combine skincare with a healthy lifestyle.** The authors emphasize that a balanced diet and healthy lifestyle significantly enhance the benefits of anti-aging skincare. 1. **Be patient and consistent.** Herbal extracts are viewed as milder and more compatible with skin physiology than synthetic alternatives. They may work more gradually. Patients should also be aware that the global anti-aging market reached an estimated $216 billion in 2021. This growth reflects increasing consumer interest in natural, plant-derived, and "clean" skincare products. However, not all products on the market are backed by strong scientific evidence. The authors stress that more research is needed. Standardization of herbal extracts, safety testing, and clinical efficacy trials are all necessary to develop useful, science-based natural anti-aging remedies. Until then, patients should choose products from reputable brands and consult with dermatologists or healthcare providers about their skincare routines. ## Frequently Asked Questions ### What plant ingredients might actually help my aging skin? The review lists several with documented benefits: green tea polyphenols (EGCG) reduce oxidative damage and improve elasticity; aloe barbadensis miller retains moisture and supports wound healing; chamomile extract improves moisture retention and cell connections; Centella asiatica increases hydration and regeneration; hyaluronic acid holds large amounts of water; vegetable oils create a protective barrier; resveratrol and flavonoids provide antioxidant protection. ### Can herbal skincare replace my sunscreen? No. The review states that UV radiation is a major driver of skin aging, and herbal extracts with photoprotective properties may supplement, but not replace, sunscreen. Sun protection remains essential because UV exposure induces enzymes that break down collagen, fibronectin, and elastin, accelerating visible aging. Use sunscreen as your primary defense and consider plant extracts as an addition. ### How do plant extracts moisturize the skin? Plant extracts contain polysaccharides and glycosides with hydroxyl groups that retain water through hydrogen bonding, plus vegetable oils that form a barrier film and reduce water loss. For example, aloe's acetylated mannan retains moisture, alginate absorbs ambient moisture and creates a protective structure, and green tea's proanthocyanidins enhance moisture retention in the stratum corneum, improving hydration and elasticity. ### Are herbal skincare products safer than synthetic ones? The review describes herbal preparations as milder, more compatible with skin physiology, and generally less likely to cause adverse reactions than synthetic alternatives. However, it also notes that not all products on the market are backed by strong scientific evidence, and more research is needed on standardization, safety, and clinical efficacy. Patients should choose reputable brands and consult a dermatologist. ### What does it mean that the anti-aging market reached $216 billion in 2021? This figure reflects rapid growth in consumer interest in natural, plant-derived, and clean skincare products, driven by awareness and an aging global population. It does not mean all products are effective. The review stresses that many lack strong scientific backing and that standardization, safety testing, and clinical trials are still needed before natural anti-aging remedies can be considered science-based. ### How do antioxidants in plant extracts protect my skin? Plant polyphenols, flavonoids, resveratrol, and curcumin scavenge free radicals and reactive oxygen species that cause oxidative stress. They donate hydrogen or electrons to stabilize these molecules, inhibit enzymes that produce them, chelate metals like iron and copper, and activate the Nrf2-ARE pathway, which boosts the body's own antioxidant enzymes such as superoxide dismutase, catalase, and glutathione peroxidase. ### What are the limitations of the evidence for herbal anti-aging skincare? The review is a summary of other studies, not a clinical trial. It covers articles from 2000 to 2025, used only two databases, and many cited studies are laboratory cell studies rather than human trials. It provides no specific dosages, treatment durations, or statistical significance for most findings. The authors emphasize that the evidence base is still developing and more research is needed. ### I'm thinking about using herbal anti-aging skincare — when should I get a second opinion before committing to a routine? Consider a second opinion when a product's claims go beyond documented effects. Evidence supports green tea polyphenols, chamomile, Centella asiatica, aloe vera, and hyaluronic acid for moisturizing and barrier repair, and polyphenols, flavonoids, resveratrol, and curcumin for antioxidant protection. Most cited findings come from laboratory cell studies, not human trials, and specific dosages, durations, and statistical values are largely absent. Herbal extracts may supplement, not replace, sunscreen. A clinician can review your routine and skin concerns. Diagnostic Detectives Network provides independent expert second opinions. ## Source Information **Original article title:** Aging and Herbal Interventions: Mechanistic Insights and Therapeutic Potential. **Authors:** Suvedi D, Kumar A, Kalia S, Kumar A, Koul S, James A, Kumar D, Nagraik R, Gulilat H. **Author affiliations:** Faculty of Applied Sciences and Biotechnology, Shoolini University, Solan, Himachal Pradesh, India; Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh, India; Department of Biotechnology, School of Applied and Life Sciences, Uttaranchal University, Dehradun, India; Polish Academy of Sciences, Institute of Biochemistry and Biophysics, Warsaw, Poland; Department of Biotechnology, Graphic Era (Deemed to Be University), Dehradun, India; Department of Biomedical Sciences, Institute of Health, Jimma University, Jimma, Oromia, Ethiopia **Corresponding author:** Henok Gulilat (henok.gulilat@ju.edu.et) **Journal:** Journal of Cosmetic Dermatology, 2025; 24:e70335 **Publication details:** Received 4 December 2024; Revised 5 June 2025; Accepted 25 June 2025 **DOI:** https://doi.org/10.1111/jocd.70335 **Funding:** The authors received no specific funding for this work. *This patient-friendly article is based on peer-reviewed research.* --- Publisher: Diagnostic Detectives Network (https://diagnosticdetectives.com) — independent multi-expert medical second opinions, worldwide, private-pay. 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