Genetic profiling of tumors improves cancer treatment. How genetic ancestry DNA tests help in cancer therapy selection?
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Genetic DNA ancestry information influences response to treatment. Dr. Esteban G. Gonzalez, MD. Genetic DNA ancestry DNA tests and precision medicine are widely used in medicine. Dr. Anton Titov, MD. Genetics plays role in side effects of medications. Genetic DNA ancestry is important at the individual gene level. Genetic DNA ancestry tests and precision medicine is a future of cancer treatment. Precision medicine helps to determine response to medications. Dr. Esteban G. Gonzalez, MD. Personalized medicine helps to treat breast cancer. Precise molecular diagnosis of breast cancer is precision medicine. Video interview with top expert in medical genetics and asthma. Medical second opinion confirms that breast cancer diagnosis is correct and complete. Medical second opinion ensures that genetic DNA ancestry information is included in diagnosis of breast cancer (BRCA1 and BRCA2). Medical second opinion also helps to choose the best personalized treatment strategy for breast cancer. Seek medical second opinion on breast cancer and be confident that your precision medicine treatment is the best. Dr. Esteban G. Gonzalez, MD. Genetic DNA ancestry test and precision medicine. Medical Second Opinion. You published in Nature in 2011 that 96% of all genome wide association studies are done around the world. 96% of studies are done on people of European DNA ancestry. That’s correct. Your work shows that ancestral DNA information determines individual response to the medications. But it’s not just about broad racial groups. It’s all about the ancestral DNA information. It is the genetic information at the individual gene level. You showed that it is the individual DNA ancestry information. Dr. Anton Titov, MD. It makes the most impact at the gene level. Individual genetic DNA ancestry determines how individual responds to the medications. Genetic DNA ancestry determines the likelihood of side effects. Yes. Dr. Anton Titov, MD. How can Genetic DNA ancestry information be applied in precision medicine? Medical Second Opinion (Professor of Pharmacogenomics, UCSF). We are doing that already today. For certain tumors we will measure the genetics of the tumor. Based upon your test results we might give you one medication or another medication. Or we might give you adjuvant cancer therapy based upon your gene expression pattern. Right now we classify breast cancer to stage 1, stage 2, stage 3, and stage 4. But that was based on old classification system. Now we can look at tumor gene expression pattern. Dr. Esteban G. Gonzalez, MD. This is in addition to giving you the classic tumor staging. We can we can tell you if you would benefit from additional chemotherapy. That is new and cutting-edge. That is occurring right now. It’s FDA-approved. Genetic DNA ancestry tests and precision medicine. Cancer treatment based on DNA ancestry of individual genes provides best results. Know your genetic DNA ancestry.