Transcript of video
What advances in stage 4 colon cancer treatment can we expect? Education of doctors about benefits of liver and lung metastases resection is important. Patients with metastatic colon cancer can achieve for long-term survival. Cure of stage 4 colon cancer patient is possible. Precision surgery and precision chemotherapy based on the genetic tumor markers. Assessment of evolution of colon cancer tumor in real time. Best treatment for colon cancer stage 4. Dr. Anton Titov, MD. The future. Dr. Graeme Poston, MD. Metastatic liver colon cancer must be treated surgically. Doctors must resect metastases in treatment of stage 4 colon cancer. Liver metastases resection must be done in stage 4 advanced colorectal cancer. Video interview with leading British liver cancer surgeon specializing in colorectal cancer metastases resection. Patients must search for best liver cancer surgeon and colorectal surgeon on internet. Dr. Graeme Poston, MD. Colorectal cancer liver metastases treatment is possible. Advanced stage 4 colon cancer surgery for liver metastases must be widely available. Medical second opinion confirms that stage 4 colorectal cancer diagnosis is correct and complete. Dr. Anton Titov, MD. Medical second opinion also confirms that liver metastases surgery is possible in stage 4 colon cancer. Best treatment for advanced stage 4 colon cancer with liver metastatic lesions is surgery, chemoembolization, SIRT, TACE DEBIRI and irreversible electroporation of colon cancer metastases. Medical second opinion helps to choose the best treatment for stage 4 colorectal cancer with liver metastases. Get medical second opinion on advanced colorectal cancer and be confident that your treatment is the best. Best colorectal cancer treatment center for liver metastases. Dr. Graeme Poston, MD. Video interview with leading expert in colorectal cancer liver metastases treatment surgery. Best treatment for colon cancer stage 4. What is the future? Dr. Anton Titov, MD. Colorectal cancer treatment has changed dramatically over the last decade. In particular, stage 4 metastatic colorectal cancer treatment has achieved remarkable progress. Yes. We spoke at length about liver metastases treatment in colon cancer patients. It is a very exciting field. Dr. Anton Titov, MD. How do you see the future of colorectal cancer therapy? What advances in stage 4 metastatic colorectal cancer treatment will be possible? What new advances we can expect in the next several years? Dr. Graeme Poston, MD. Leading liver cancer surgeon. Well, the first thing is still education. It is still convincing other doctors that resection of liver metastases in stage 4 colon cancer patients is worth doing. vThere are still huge gaps in knowledge amongst doctors. Many doctors still think. “Oh, my God! Cancer is in the liver. You’re going to die.” Many doctors then do nothing to treat patients with advanced metastatic colon cancer. Dr. Anton Titov, MD. This is a very important point. Because for many diseases it is known that the majority of patients do not get state-of the-art treatment of their disease. That includes metastatic colon cancer. I would just like to emphasize this point. Dr. Graeme Poston, MD. Leading liver cancer surgeon. Yes. Well, we have studied that in the United Kingdom. We found that outdated attitude of many doctors to metastatic stage 4 colon cancer treatment. Dr. Graeme Poston, MD. We have measured it. We have measured doctors’ attitudes. We measured how doctors behave with patients who have advanced cancer. We published our results. We have shown that there are many doctors, surgeons, colorectal surgeons. They still don’t believe that operating on the liver in metastatic colon cancer is a good thing to do. Dr. Anton Titov, MD. Despite all the data? The data shows that resection of liver metastases in stage 4 colon cancer improves patient’s survival and quality of life. Dr. Graeme Poston, MD. Leading liver cancer surgeon. Despite all the data! I have told doctors around the world to repeat those clinical trials that we have done. You repeat clinical trials on liver metastases resection in stage 4 advanced colon cancer treatment in Russia. Dr. Graeme Poston, MD. You will find the same result. You repeat them in the United States, you have the same result. Doctors just don’t understand what you can now do for advanced colon cancer patients. Many doctors have not progressed in 30 years in understanding how to treat advanced colorectal cancer with liver metastases for best results. Dr. Anton Titov, MD. Perhaps, it is time for colon cancer patients to become more active and demand the state-of-the-art colon cancer treatment? Dr. Graeme Poston, MD. Leading liver cancer surgeon. This is why the Internet is very important. Patients can actually look at the best treatment methods for colon cancer treatment. Dr. Anton Titov, MD. Patients can find on the internet about the best methods to treat stage 4 colon cancer. Patients can say. “Why can I can get these results at that hospital? But my doctor at my hospital says that it is not possible?” That is the first thing. Dr. Graeme Poston, MD. That will be a major step in the correct direction to cure more patients with advanced colon cancer. That will push a major improvement in outcome of treatment for metastatic stage 4 colon cancer. The second crucial goal is this. We are getting more and more surgeons trained to do resection of liver metastases in patients with advanced colorectal cancer. Surgery to remove colon cancer metastases from the liver is not easy. But more and more surgeons are trained to do that operation. I started doing resection of liver metastases in stage 4 colon cancer patients 25 years ago as a surgeon in Liverpool. We had three patients in England doing this surgery. We have now got 150 liver surgeons doing metastatic lesion resections. We still haven’t got enough surgeons to treat all patients who need surgical operation to treat liver metastases. It is important to get the young surgeons. Dr. Graeme Poston, MD. They must train how to do resection of liver metastases in advanced colon cancer patients. It is also important to establish more multi-disciplinary teams. Dr. Anton Titov, MD. They must work on treatment of advanced metastatic colorectal cancer. It is a legal requirement to use multidisciplinary teams to make treatment plans for cancer patients in Britain, in France, in Belgium, in Spain, in Scandinavia, the Netherlands, Ireland. But there is no legal requirement to have multi-disciplinary cancer treatment team in Germany. It is not a requirement in Italy. Multidisciplinary team assessment of a cancer patient is not required in a lot of countries around the world. Dr. Graeme Poston, MD. Leading liver cancer surgeon. I do a lot of work in China. I have been in China twice this year. I will go back to China in November. We ran workshop in Shanghai about how to build a multi-disciplinary cancer treatment team for colorectal cancer patients. It was over-subscribed. Doctors are clamoring for this kind of knowledge. How to make an MDT, multidisciplinary team. How to make it work for best colon cancer treatment results. That will be the major step forward. We have to integrate the MDT outcomes. Dr. Anton Titov, MD. We must make sure that we are using the best treatment. The last thing is probably equally important. Dr. Anton Titov, MD. It will be the precision surgery based on the genetic tumor markers. Precision surgery will be based on genetic behavior of the patient’s colon cancer tumor. Dr. Graeme Poston, MD. We can direct the correct treatment to the correct patient. Choice of treatment is based upon the colon cancer tumor mutation status. I’m convinced that by 2020, we will have that treatment approach. Dr. Anton Titov, MD. It is precision medicine and precision surgery. They are matched to each other. Dr. Graeme Poston, MD. Leading liver cancer surgeon. Yes. Yes. Dr. Anton Titov, MD. I spoke to Professor David Kerr of Oxford University. We discussed the precision medicine. We discussed the use of colon cancer tumor markers both in the tumor and in the patient. Dr. Graeme Poston, MD. Leading liver cancer surgeon. Yes. Yes. Yes. Dr. Anton Titov, MD. It is all coming together. Precision medicine and precision surgery. This gets best treatment results for colon cancer patients. Dr. Graeme Poston, MD. Leading liver cancer surgeon. It is all coming together. Dr. Anton Titov, MD. Professor Poston, thank you very much for this very interesting conversation about very exciting future for the colorectal cancer treatment. In particular, it was great to discuss surgical treatment of liver metastatic disease in patients with stage 4 colorectal cancer. Dr. Graeme Poston, MD. That gives a lot of hope to patients. Thank you very much. My pleasure. Thank you very much. Dr. Graeme Poston, MD. Leading liver cancer surgeon. Dr. Anton Titov, MD. Thank you. Best treatment for colon cancer – you must treat metastatic colon cancer very aggressively. Cure or long-term survival in stage 4 colon cancer is possible.