Both genetic profile of colon cancer tumor AND genetic makeup of the patient are important in treatment plan selection. Modern colon cancer tumor profile panels assess 40 to 400 genetic mutations (and KRAS NRAS, BRAF, MSI markers). Genetic analysis of patients helps to predict treatment toxicity, chemotherapy response and people at risk for colorectal cancers.
Genetic profile of patient is equally important to genetic profile of the cancer tumor. How genetic variations in patient’s cells affect response to treatment in colorectal cancer? Why it’s important to analyze patient’s genome to select best cancer therapy? Leading colorectal cancer chemotherapy expert discusses precision medicine treatment of colorectal cancer.